Depression

Depression is an illness that involves our feelings, our thinking, and our senses. It undermines self confidence and changes the way we view the world. People diagnosed with major depression show a combination of symptoms that interfere with the ability to work, study, sleep, eat, and enjoy once pleasurable activities.

Depression is very common. Embarrassment and shame at "being weak" is the most common reason for not seeking help. Depression is a medical illness and is not due to a weak personality.

Depression interferes with everyday functioning and causes pain and suffering, not only to those who are ill, but also to family and friends. Serious depression can destroy family life and ruin the life of the individual who is depressed.

Depression starts at any age (mean age 27).  Worldwide, it accounts for 12 per cent of all disability. The majority of suicides are due to depression. Depression interferes with everyday functioning and causes pain and suffering, not only to those who are ill, but also to family and friends. Serious depression can destroy family life and ruin the life of the individual who is depressed.

Depression will soon be the leading disease burden to the economy in the western world, on par with heart disease. In any given year, 10 percent of the population suffers from a depression. Depression is also one of the largest markets in the world: $20 billion market and growing rapidly for many reasons including: better diagnosis and treatment, its correlation to the aging population and, perhaps, the greater psychological demands of people at work and home.

Our CLR3001 Phase II compound has a unique antidepressant mechanism of action.

We also have preclinical new chemical entities in the CLR300 series with unique receptor binding profiles.